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THE PHARMA REVIEW (JULY AUG 2018)

Spores Do Not Have an Intrinsic D-value

John R. Gillis, Ph.D.

Introduction: A major misunderstanding in the industry is that spores have an intrinsic D-value. This is not true if for no other reason than it is impossible to test the resistance of individual spores suspended in space. The spores are placed onto a surface or suspended in liquid and this system becomes the biological indicator (BI). It is the resistance of the system that is measured, not simply the spores.

 

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