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THE PHARMA REVIEW (JULY AUG 2018)

Natural Flavonoids and Its Pharmaceutical Importance

Sankhadip Bose*1, Dhrubajyoti Sarkar1, Abhijit Bose2 & Subhash Chandra Mandal3

Introduction: Flavonoids (or bioflavonoid), which is known as Vitamin P and citrin, are a type of secondary metabolites from plants, ubiquitous in photosynthesizing cells and are usually found in fruits, vegetables, nuts, seeds, stems, flowers, tea, wine, propolis and honey. For centuries, preparations containing these compounds as the principal physiologically active constituents have been used to treat human diseases. The most important groups of secondary metabolites in plants, flavonoids, are also the better sources of natural antioxidants in human diets. So, flavonoids can be used as a unique constituent in the control of different human diseases. It has polyphenolic structure, for that it become responsible for different pharmacological activities. The antioxidant effect of flavonoids is due to their Hydroxyl groups, by scavenging free radicals or by chelating metal ions. The prevention of radical generation that damage the biomolecules leading to oxidative stress can be protected by flavonoids and it also gives security against the many diseases such as cancer, cardiovascular and respiratory disorders, arthritis and early ageing. The present review deals with the structural aspects of flavonoids and their protective roles against many human diseases.

 

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